Apply implicit differentiation by taking the derivative of both sides of the equation with respect to the differentiation variable
The derivative of the linear function is equal to $1$
The derivative $\frac{d}{dx}\left(x^{\frac{4}{x}}\right)$ results in $4\left(1-\ln\left(x\right)\right)x^{\left(\frac{4}{x}-2\right)}$
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